Program Thursday, June 3
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08.30-10.00 Parallel sessions

Session 24 (Branding)
Neuronal trafficking: the long and winding road that leads to the synapse
Chairpersons: Huib Mansvelder (Amsterdam) and Gerard Borst (Rotterdam)
Ben Oostra (Rotterdam): Fragile X syndrome and neuronal deficits (30) (pdf)
Niels Galjart (Rotterdam): Visualizing vesicle transport in cultured neurons using a novel imaging technique (15) (pdf)
Ruud Toonen (Amsterdam): Analysis of secretory granule movement in wildtype and munc18-1 null mutant chromaffin cells with evanescent wave microscopy (15) (pdf)
Eckart Gundelfinger (Magdeburg, Germany): Role of Piccolo and Bassoon in assembling and organizing the active zone of neurotransmitter release (30) (pdf)

Session 25 (Doorwerth)
Amyotrophic lateral sclerosis
Chairpersons: Dick Jaarsma (Rotterdam) and Freek van Muiswinkel (Utrecht)
(sponsored by 'ALS Centrum Nederland')
Georg Haase (Marseille, France): Mechanisms on neuronal death and survival in ALS (30) (pdf)
Eva Teuling (Rotterdam): Lessons from a decade of SOD1-ALS mice: a neuropathological perspective (15)
Joost Verhaagen (Amsterdam): Induction of Sema3A expression in an ALS mouse model (15)
Ludo van den Bosch (Leuven, Belgium): Excitotoxicity and inflammation in ALS (15) (pdf)
Liselijn Wisman (Utrecht): Towards gene therapy in ALS (15) (pdf)

Session 26 (Patio)
Hearing and deafness
Chairperson: Hikke van Doorninck (Rotterdam)
Hikke van Doorninck (Rotterdam): Gata3 mouse is a model for the human HDR deafness syndrome (30) (pdf)
Theo Peters (Nijmegen): Hearing loss caused by transport disorders in the inner ear (15) (pdf)
Sjaak Klis (Utrecht): Cisplatin-induced hearing loss: mechanisms, recovery and protection (15) (pdf)
Sietse van Netten (Groningen): Transduction channels in cochlear hair cells (15) (pdf)
Hannie Kremer (Nijmegen): A mutation in the gamma actin 1 (ACTG1) gene causes autosomal dominant hearing loss (DFNA20/26) (15) (pdf)

Session 27 (Gelderland)
Inflammatory responses
Chairpersons: Cobi Heijnen and Frank van Bel (Utrecht)
Stuart Allan (Manchester, UK): Inflammatory processes in brain injury (30) (pdf)
Annemieke Kavelaars (Utrecht): Regulation of G-protein-coupled receptor kinases in hypoxic-ischemic brain injury (15) (pdf)
Erik Boddeke (Groningen): Chemokines in brain injury (15) (pdf)
Annemarie van Dam (Amsterdam): Pro- and anti-inflammatory cytokines in neuroinflammation: focus on IL-b and IL-10 (15) (pdf)
Cacha Peeters (Utrecht): Clinical and molecular aspects of NO inhibition in neonatal hypoxia-ischemia (15) (pdf)

09.30-10.30 Satellite session Neuropsychology (part 1) (Renkum)
Cognitive, emotional, and behavioral changes in elderly
(organized by the Dutch Society for Neuropsychology)

10.00-12.00 Poster session Neuroscience 2 (Branding)

11.00-12.30 Satellite session Neuropsychology (part 2) (Renkum)
Risk factors, course, and intervention of cognitive, emotional and behavioural changes in patients with acquired brain lesions
(organized by the Dutch Society for Neuropsychology)

12.00-12.45 Session 28 (Branding)
Neurofederation Lecture
Chairperson: Arjen Brussaard (Amsterdam)
Jeff Lichtman (St. Louis, MO, USA): In vivo monitoring of axons and synapses in fluorescent mice (pdf)

12.45-14.00 Lunch (Pailjon)

14.00-15.30 Parallel sessions

Session 29 (Branding)
Synaptic function and plasticity
Chairpersons: Ype Elgersma and Christian Hansel (Rotterdam)
Hey-Kyoung Lee (College Park, MD, USA): Regulation of AMPA receptors in synaptic plasticity (30) (pdf)
Alfredo Kirkwood (Baltimore, MD, USA): Control of synaptic plasticity in visual cortex. (30) (pdf)
Michel Brecht (Rotterdam): Deciphering cortical codes for movement by intracellular stimulation (15) (pdf)
Christian Hansel (Rotterdam): Cerebellar long-term potentiation: a synaptic candidate mechanism for forgetting (15) (pdf)

Session 30 (Doorwerth)
Adult neurogenesis and depression
Chairpersons: Paul Lucassen and Marian Joëls (Amsterdam)
Paul Lucassen (Amsterdam):
Structural brain changes in major depression  (15) (pdf)
Boldizsar Czeh (Gottingen, Germany): Stress-induced structural alterations in the hippocampus: reversal by antidepressants?
(30) (pdf)
Alexa Veenema (Regensburg, Germany): Changes in proliferation in low and highly aggressive mice
in relation to inborn alterations in HPA axis activity (15) (pdf)
Thomas Oosting (Utrecht):
Effects of maternal separation on apoptosis related gene expression and adult neurogenesis (15) (pdf)
Thomas Steckler (Beerse, Belgium): Developing antidepressant treatment strategies involving modulation of neurogenesis (15) (pdf)

Session 31 (Gelderland)
Amyloid-ß and Alzheimer's disease
Chairpersons: Wiep Scheper en Elly Hol (Amsterdam)
Hilal Lashuel (Boston, MA, USA): Protein fibrillogenesis in Alzheimer's disease: separating the culprits from the innocent bystanders (30) (pdf)
Sidhartha Chafekar (Amsterdam): Cellular models for amyloid-ß toxicity (15) (pdf)
Rob Veerhuis (Amsterdam): Extracellular amyloid-ß associated proteins in AD (15) (pdf)
Micha Wilhelmus (Nijmegen): Small heat shock proteins stimulate amyloid-ß protein aggregation and inhibit cerebrovascular amyloid- toxicity (15) (pdf)
Annemieke Rozemuller (Amsterdam): Amyloid-ß-associated proteins in CAA (15) (pdf)

Session 32 (Patio)

Monitoring neurotransmitters in goal-directed behavior
Chairperson: Matthijs Feenstra (Amsterdam)
Paul Phillips (Chapel Hill, NC, USA): Subsecond dopamine changes during reward-related behavior (30) (pdf)
Arjen van Ooyen (Amsterdam): DA and models of reinforcement learning (15) (pdf)
Jamilja van der Meulen (Amsterdam): Prefrontal DA release and cognitive flexibility (15) (pdf)
Dilek Karakuyu (Bochum, Germany): Dopaminergic and serotonergic modulation of working memory (15) (pdf)
Wietse Oldenziel (Groningen): Development of microsensors for glutamate in the CNS (15) (pdf)

Satellite session Neuropsychology (part 3) (Renkum)
Neuropsychiatry in adults and children
(organized by the Dutch Society for Neuropsychology)

15.30-16.00 Break

16.00-17.00 Session 33 (Branding)
Society of Experimental and Clinical Neuroscience (EKN) keynote lecture
Chairperson: Bart Ellenbroek (Nijmegen)
Terry Robinson (Ann Arbor, MI, USA): Drugs, neuroplasticity and the transition to addiction (pdf)

Poster Award Ceremony Neuroscience 2

17.00-18.30 Parallel sessions

Session 34 (Doorwerth)
Epileptogeneity of brain lesions
Chairpersons: Frans Leijten (Utrecht) and Rob Voskuyl (Leiden)
(organized and sponsored by 'SWO Liga tegen Epilepsie')
Diane Chugani (Detroit, USA): Neurochemical characteristics of epileptogenic lesions: PET experience (30) (pdf)
Else Tolner (Amsterdam): Progression of epileptogenesis in kainic acid laesioned rat brain: studies on parahippocampal synaptic reorganization (15) (pdf)
Floor Jansen (Utrecht): Consistency of epileptogenic foci in patients with tuberous sclerosis (15) (pdf)
Saskia van der Hel (Utrecht): Reduced glutamine synthetase in the hippocampus of patients with temporal lobe epilepsy is associated with neural loss (15) (pdf)
Cyrille Ferrier (Utrecht/Amsterdam): Histological correlates of epileptogeneity in human ganglioglioma (15) (pdf)

Session 35 (Branding)
The blood-brain barrier in neurological diseases
Chairperson: Elga de Vries (Amsterdam)
Raj Kalaria (Newcastle, UK): Cerebrovascular abnormalities in Alzheimer's disease (30) (pdf)
Gerty Schreibelt (Amsterdam): Redox regulation of monocyte migration across the blood-brain barrier (15) (pdf)
Liesbeth de Lange (Leiden): In vivo monitoring of blood-brain barrier functionality in relation to extracellular messenger compounds in the cortical stimulation model (15) (pdf)
Bert de Boer (Leiden): Blood-brain barrier functionality, disease and drug targeting (15) (pdf)
Paula Jansen (Maastricht): Apolipoprotein E affects cholesterol homeostasis in the brain (15) (pdf)

Session 36 (Patio)
Modelling of memory and psychopharmacology
Chairperson: Arjen Blokland (Maastricht)
Kim Kuypers (Maastricht): The effects of MDMA on verbal memory (15) (pdf)
Martijn Meeter
(Amsterdam): Acetylcholine and learning mode: the slow shift account (15) (pdf)
Elke Weezenberg
(Nijmegen): Effects of Biperiden and Rivastigmine on memory and visuospatial processes (15) (pdf)
Joyca Lacroix (Maastricht): Modeling visual recognition memory with natural input (15) (pdf)
Michael Hasselmo (Boston, MD, USA): Modeling the role of acetylcholine and hippocampal theta rhythm in memory function (30) (pdf)

Session 37 (Gelderland)
Startle modulation and neuropsychiatric disorders
Chairpersons: Lucianne Groenink and Anneloes Dirks (Utrecht)
Peter Lang (Gainesville, FL, USA): Measuring emotion: the startle probe reflex (30) (pdf)
Reinoud de Jongh (Utrecht): Fear versus anxiety: sex, drugs and neural pathways (15) (pdf)
Bart Ellenbroek (Nijmegen): Gene*environment interactions in the development of prepulse inhibition (30)
(pdf)
Anneloes Dirks (Utrecht): Prepulse inhibition and human neuropsychiatric disorders (15)
(pdf)

19.00 Dinner

21.00-21.45 Session 38 (Branding)
Netherlands Society for Psychonomics (NVP) keynote lecture

Chairperson: Jaap Murre (Amsterdam)
Robert Stickgold (Boston, MD, USA): Cognitive neuroscience of waking, sleeping and dreaming
 

 
ENP2004 program Thursday