PROGRAM

afternoon

08.30     Plenary session    

• Session 6
  OF ORPHANS AND THEIR KINDRED
  Moderator: Onno Bakker (Amsterdam)
  Bart Staels (Lille, F)   
  Peroxisome proliferator-activated receptors (PPARs): nuclear receptors at the crossroads between lipid metabolism and inflammation

09.15    Parallel sessions
             with break between 10.15-10.45

• Session 6 (continuation)
  OF ORPHANS AND THEIR KINDRED
  Moderator: Onno Bakker (Amsterdam) 
  Guido Jenster (Rotterdam)
  Co-activators and co-repressors as mediators of nuclear receptor action (30)
  Behrouz Zandieh Doulabi (Amsterdam)
  TRbeta1 in liver: a new view (30)
  Hanneke Assies (Amsterdam)
  PPARs, PUFA and psychiatry (30)
  André Uitterlinden (Rotterdam)
  Genetic variations in steroid receptor genes (30)
      
• Session 7
  GROWTH FACTOR SIGNALING
  Moderators: Ger Strous and Paul van Bergen en Henegouwen (Utrecht)
  Patrick Mayeux (Paris, F)
  The mechanisms of phosphatidylinositol 3-kinase activation by the receptors for erythropoietin and thrombopoietin (30)
  Ger J. Strous (Utrecht)
  Ubiquitination and downregulation of the growth hormone receptor (30)
  Jeroen den Hertog (Utrecht)
  Structure and function of receptor protein-tyrosine phosphatase-a (30)
  Paul van Bergen en Henegouwen (Utrecht)
  Regulation of the serine/threonine kinase PKB/Akt (30)
        
• Session 8
  NEUROPEPTIDES AND FOOD AND WATER INTAKE
  Moderator: Roger Adan (Utrecht) 
  Joel Elmquist (Harvard, USA)
  CNS circuitry involved in energy balance (45)
  Koert de Vries (Groningen)
  Leptin signaling cascade (15)
  Martien Kas (Utrecht)
  Upregulation of the central melanocortin system in activity-induced anorexia (30)
  Marga Nijenhuis (Utrecht)
  Mutations in the vasopressin prohormone involved in diabetes insipidus impair endoplasmic reticulum export but not sorting (30)
        
• Session 9
  MELATONIN, THE DARK HORMONE OF THE MILLENNIUM
  Moderator: Dries Kalsbeek (Amsterdam) 
  Ruud M. Buijs (Amsterdam)
  Pathways and mechanisms that control melatonin secretion (30)
  Paul Pevet  (Strasbourg, F)
  Melatonin and the neuroendocrine control of seasonal rhythms (30)
  Elsbeth E. Nagtegaal (Bennekom)
  Melatonin treatment of delayed sleep phase syndrome and shift work (30)
  Debra Skene (Guilford, UK)
  Sleep and melatonin rhythms in the blind (30)

• Session 10
  MODERN TECHNIQUES IN ENDOCRINOLOGY AND NEUROSCIENCES
  Moderators: Fred van Leeuwen (Amsterdam) and Eric Roubos (Nijmegen)
  Peter Nielsen (Copenhagen, DK)
  Possibilities and impossibilities of peptide nucleic acids (PNAs) 
  (sponsored by Promega Corporation, Bio-Rad, B&L Systems and Biosource)

12.30    Lunch

13.30    Parallel sessions

• Session 10 (continuation)
  MODERN TECHNIQUES IN ENDOCRINOLOGY AND NEUROSCIENCES
  Moderators: Fred van Leeuwen (Amsterdam) and Eric Roubos (Nijmegen)
  (sponsored by Promega Corporation, Bio-Rad, B&L Systems and Biosource)
  Andrew Dixon (Hemel Hempstead, UK)
  Multiphoton microscopy, a new way to study  neuroendocrine tissue (45)
  Ian Humphery-Smith (Utrecht)
  Pharmaceutical proteomics: state of the art (45)
  Oscar Schoots (Utrecht)
  What to do after a scientific discovery? (30)
     

• Session 11
  Biological components of neuronal disease (1)  
  COMMON MECHANISMS IN NEUROGENESIS AND NEURONAL APOPTOSIS
  Moderators: Paul Lucassen (Amsterdam) and Erno Vreugdenhil (Leiden) 
  Paul Lucassen (Amsterdam)
  An introduction to the overlap between cell birth and cell death in brain disorders (15)
  Henriëtte van Praag (La Jolla, CA, USA)
  Regulation of neurogenesis in the adult hippocampus (45)
  Marieke Kruidering (San Francisco, CA, USA)
  Neuronal death and survival: the role of (CAM) kinases (30)
  Teun Holtmaat  (Amsterdam)
  The role of semaphorins in structural plasticity of hippocampal circuits (30)
       
• Session 12
  Cognition: from basic to clinical science (1)  
  THE HIPPOCAMPUS AND PREFRONTAL CORTEX IN COGNITION AND MEMORY
  Moderator: Cyriel Pennartz (Amsterdam) 
  Menno Witter (Amsterdam)
  Anatomy of hippocampal and prefrontal connectivity in rats and primates (30)
  Janice Muir (Cardiff, UK)
  The frontal cortex and the hippocampus in learning, memory and attention in the rat
  Tonny Mulder (Amsterdam) (30)
  Neural correlates of learning and memory in rat prefrontal cortex (15)
  Eddy van der Zee (Groningen)
  Interactions between stress hormones, learning and neural plasticity in the hippocampus (15)
  Serge Rombouts (Amsterdam)
  fMRI studies on hippocampal activation (15)
  Jan de Bruin (Amsterdam)
  Roles of rat hippocampus and prefrontal cortex in place and response learning (15)
       
• Session 13
  Fundamental basis of psychiatry (1)  
  PSYCHOENDOCRINOLOGY IN CHILDREN
  Moderator: Jan Buitelaar (Utrecht) 
  Patricq Kamphuis (Utrecht)
  Prenatal exposure to dexamethasone in rats (45)
  Anja Huizink (Utrecht)
  Prenatal stress, HPA-axis and postnatal development of children (15)
  Heddeke Snoek (Utrecht)
  Serotonergic system, HPA-axis and aggression in children: results from a sumatriptan challenge (15)
  Carolina de Weerth (Utrecht)
  Prenatal stress and infant development (15)
  Stefanie van Goozen (Utrecht)
  Androgenic hormones in children with aggressive behavior (15)
       
• Session 14
  Functional imaging (1)
  APPLICATION OF IMAGING IN EPILEPSY SURGERY
  Moderators: Frans S.S. Leijten (Utrecht) and Pauly Ossenblok (Heeze) 
  (sponsored by Netherlands League against Epilepsy)
  Hermann Stefan (Erlangen, D)
  Trends and developments in functional imaging for epilepsy surgery (30)
  Rik Stokking (New Haven, USA)
  Subtraction SPECT for epilepsy surgery at Yale (15)
  Pauly Ossenblok (Heeze)
  Localisation of epileptiform discharges using EEG, MEG and MRI (15)
  Geertjan Huiskamp (Utrecht)
  Measurement, modelling and simulation of the EEG, MEG and ECoG (15)
  Eric Achten (Gent, B)
  MRS in temporal lobe epilepsy (15)
  Fernando H. Lopes da Silva (Amsterdam)
  Imaging absences of consciousness (30) 
       
• Satellite meeting
  Leiden/Amsterdam/Groningen Biological Rhythm Group (part 1)
  Click here for program

15.30    Break 

16.00    Parallel sessions 

• Session 15
  Biological components of neuronal disease (2)
  NEURO-IMMUNOMODULATION     
  Moderators: Inge Huitinga (Amsterdam) and Eric Boddeke (Groningen)
  Richard Horuk (Richmond, CA, USA)
  Chemokine and chemokine receptor expression in the central nervous system (45)
  Knut Biber (Groningen)
  Neuronal expression of the chemokine SLC associated with neurodegeneration (30)
  Corline J.A. De Groot (Amsterdam)
  Chemokine expression in the central nervous system during multiple sclerosis (15)
  Anne-Marie van Dam (Amsterdam)
  Expression of neuronal IL-1ß in the rat hypothalamus (30)
       
• Session 16
  Cognition: from basic to clinical science (2)
  THE THALAMUS AND COGNITION     
  Moderators: Ysbrand van der Werf  (Amsterdam) and Laus Broersen (Wageningen)
  Chairpersons: Menno Witter (Amsterdam) and Jelle Jolles (Maastricht)
  Henk Groenewegen (Amsterdam)
  Thalamocortical relationships (30)
  Tomas Paus (Montreal, Canada)
  Cortical excitability and the human thalamus (30)
  Laus Broersen (Wageningen)
  The role of the medial dorsal nucleus of the thalamus in selective attention: animal experimental studies (15)
  Ysbrand van der Werf (Amsterdam)
  Infarctions of the human thalamus: effects on cognition (15)
  Wouter Staal (Utrecht)
  Volume decrease of the thalamus in schizophrenia (15)
  Gilles van Luijtelaar (Nijmegen)
  The role of the reticular nucleus of the thalamus in EEG oscillations (15)
        
• Session 17
  Fundamental basis of psychiatry (2)
  RESULTS OF PSYCHIATRIC EPIDEMIOLOGY
  Moderator: Hans Ormel (Groningen)
  G.W. Brown (London, UK)
  The etiology of common mental disorders: a selective overview of major findings from psychiatric (genetic-) epidemiological studies (30)
  Hans Ormel (Groningen)
  Neuroticism: a marker of vulnerability to emotional disorder (30)
  Tineke Oldehinkel (Groningen)
  Neuroticism as vulnerability factor for depression in the elderly (15)
  Erwin Geerts (Groningen)
  Interpersonal and cognitive processes linking neuroticism and depression (15)
  Jan Neeleman (Groningen)
  Neuroticism and general liability to ill-health (30)
      
• Session 18
  Functional imaging (2)
  IN VIVO BRAIN ENERGY METABOLISM: UPDATE  AND IMAGING     
  Moderators: Jaap Korf (Groningen) and Klaas Nicolay (Utrecht)
  Gea Vogt (Groningen)
  Energy metabolite formation in and efflux from the rat brain as studied with biosensor technology (15)
  W.B.Velthuis (Utrecht)
  Neuroprotective therapy in experimental stroke, as monitored using in vivo MR (15)
  Simone J.M. Neele (Amsterdam)
  Effect of raloxifene on cerebral functions associated with Alzheimer's disease in healthy postmenopausal women (15)
  Odille A. van den Heuvel (Amsterdam)
  Neuro-imaging in obsessive-compulsive and related disorders (15)
  Kees P.J. Braun (Utrecht)
  Cerebral energy metabolism and experimental hydrocephalus, as studied using in vivo MR techniques (15)
  Pierre Magistretti (Lausanne, CH)
  Compartmentalization of brain energy metabolism: consequences for neuroimaging (45)
       
• Session 19
  HOW DO FLIES SEE THE WORLD WITH THEIR COMPOUND EYES?     
  Moderator: Doekele G. Stavenga (Groningen)
  Kentaro Arikawa (Yokohama, Japan)
  The molecular basis of butterfly pentachromatic colour vision (45)
  Hans van Hateren (Groningen)
  Neural processing of natural images by the fly visual system (45)
  Johannes Oberwinkler (Groningen)
  Calcium dynamics in microdomains in fly photoreceptor cells (30)
    
• Satellite meeting
  Leiden/Amsterdam/Groningen Biological Rhythm Group (part 2)
  Click here for program

20.30    NEUROFEDERATION LECTURE

Wijnand Geraerts (Amsterdam)
Analyzing genes for synapse formation and neuronal plasticity
(celebration of first lustrum of the Dutch Neurofederation and sponsored by Elsevier Science B.V.)
Chairperson: Fernando Lopes da Silva (Amsterdam)

21.30    Informal get-together